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Caswell, C. Han, R.

Xu, Y. Hoe, N. Nature Med. Lukomski, S.

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Squeglia, F. Acta Cryst.

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Oliver-Kozup, H. The streptococcal collagen-like protein-1 Scl1 is a significant determinant for biofilm formation by group A Streptococcus.

BMC Microbiology Olson, J. J, Thomas, J.

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J, Marazita, M. Use of 16S ribosomal RNA gene analyses to characterize the bacterial signature associated with poor oral health in West Virginia.

BMC Oral Health Reuter, M. FEMS Microbiol.

Leski, T. Identification and classification of bcl genes and proteins of Bacillus cereus group organisms and their application Weet Bacillus anthracis detection and fingerprinting.

Morgantown, WV F The streptococcal collagen-like protein-1 (Scl1) is a significant determinant for biofilm formation by group A. Morgantown escorts, female models, independent escorts, adult services, SEXY NEED DESECRET HOOKUP ANAL 69 SEX & BLOWJOB FUCK ME. Morgantown escorts, female models, independent escorts, adult services, strippers, 24 (Morgantown); Latina Exotic HAND-JOB Car BJ Anytime Sex NOT USE Hello gentlemen i am Kelsey () Looking for a local guy who will pick up me Pussy Enjoy Car 69 Fun Long Time Need 40 Dollar - 31 (Morgantown).

Mohs, A. Humtsoe, J.

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Lei, B. View more at PubMed. My research has been aimed Mirgantown understanding fundamental molecular mechanisms of bacterial pathogenesis, including adhesion and host colonization, immune evasion, and toxicity.

Additional projects are conducted in association with WVNano Initiative and include pathogen detection based on sequence polymorphisms in collagen-like genes.

The Scl1 protein selectively binds to human extracellular matrix ECM component, cellular fibronectin cFn and laminin.

GAS wild-type strains form rich biofilm on cFn-coated surface, whereas biofilms formed by scl1 mutants are significantly decreased.

Human cells deposit a cFn-rich natural ECM with distinct supramolecular structure, and GAS cells preferentially recognize and attach to this structure.

Altogether, i Scl1 surface Mofgantown is an essential determinant of GAS biofilm and ii Scl1-cFn interaction provides an adherence mechanism for biofilm stability facilitating host colonization.

Scl1 binding to LDL occurs via the apolipoprotein B component. Positions Associate Professor Organization: West Virginia University School of Medicine.

Most Significant Publications before Caswell, C. Recent Significant Publications Squeglia, F. Earlier Significant Publications Hoe, N. Media http: